SCHEMBL23729698

SCHEMBL23729698

CCCn1c(=O)c2c(C)c(C(=O)C3=C(Cl)CCCC3=O)ccc2n(C)c1=O

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPD P32754 11/20 0.38
CNR2 P34972 3/20 0.33
CNR1 P21554 1/20 0.33
TRPC5 Q9UL62 2/20 0.32
LMNA P02545 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23729701 0.90 HPD (0.39) HPDCNR2ADORA2AADORA2B
SCHEMBL23729824 0.86 HPD (0.37) HPDCNR2ADORA2AADORA2B
SCHEMBL23729826 0.85 HPD (0.38) HPDL3MBTL1
SCHEMBL23729879 0.85 HPD (0.38) HPDADORA2AADORA2B
SCHEMBL23729825 0.85 HPD (0.40) HPDADORA2AADORA2B
SCHEMBL23729328 0.84 HPD (0.36) HPDL3MBTL1
SCHEMBL23729829 0.82 HPD (0.36) HPDTRPC5ADORA2AADORA2B
SCHEMBL23729327 0.82 ALDH1A1 (0.38) HPDCNR2TRPC5LMNAADORA2A
SCHEMBL23729671 0.81 HPD (0.42) HPDL3MBTL1
SCHEMBL23730135 0.80 HPD (0.40) HPDCNR2ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858818-A1 TRIKETONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF, AND HERBICIDE Shandong Cynda Chemical Co., LTD. (CN) 2021-08-04 EP disclosed