Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616323 | 0.94 | ALDH1A1 (0.60) | ALDH1A1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL14256038 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL2625792 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HDAC1HDAC6KMT2AHPGD | |
| SCHEMBL434992 | 0.81 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL23601181 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL14158660 | 0.80 | HDAC1 (0.46) | ALDH1A1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL6211902 | 0.80 | CHRM2 (0.49) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL30832139 | 0.80 | HDAC1 (0.46) | ALDH1A1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL173280 | 0.80 | NOTUM (0.49) | ALDH1A1HDAC1HDAC6MEN1KMT2A | |
| SCHEMBL16800224 | 0.77 | HDAC1 (0.55) | ALDH1A1HDAC1HDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |