Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616323 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL23600970 | 0.83 | NLRP3 (0.42) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL23601561 | 0.82 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL23729376 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL17809604 | 0.78 | KDM1A (0.50) | NOTUMCYP11B2WDR5CHRM1 | |
| SCHEMBL434992 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL27341781 | 0.76 | NOTUM (0.43) | ALDH1A1MAPTHPGDNOTUM | |
| SCHEMBL22005067 | 0.76 | NOTUM (0.50) | ALDH1A1KMT2AMEN1NOTUMSMN1; SMN2 | |
| SCHEMBL2625792 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KMT2AHPGDNOTUMKDM4E | |
| SCHEMBL520908 | 0.74 | BRD4 (0.51) | ALDH1A1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |