Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106619 | 0.79 | PARP1 (0.37) | MAPTMAOBMEN1KMT2A | |
| SCHEMBL3600857 | 0.79 | UGT2B17 (0.36) | ALDH1A1GAAMAPTHSD17B10MAOB | |
| SCHEMBL22290260 | 0.76 | LMNA (0.37) | MAPTMAOBMEN1KMT2A | |
| SCHEMBL5535609 | 0.76 | MAOB (0.33) | ALDH1A1GAAMAPTHSD17B10MAOB | |
| SCHEMBL5535613 | 0.76 | SELL (0.39) | ALDH1A1GAAMAPTHSD17B10MAOB | |
| SCHEMBL23647751 | 0.76 | ALDH1A1 (0.31) | ALDH1A1GAAMAPTHSD17B10MAOB | |
| SCHEMBL23012562 | 0.76 | MAPT (0.35) | ALDH1A1GAAMAPTHSD17B10MAOB | |
| SCHEMBL26700316 | 0.76 | EIF4A3 (0.34) | MAPTHTR2B | |
| SCHEMBL15964739 | 0.74 | MMP12 (0.33) | HTR7HTR2BTMEM97SIGMAR1KMT2A | |
| SCHEMBL12116766 | 0.73 | NOTUM (0.34) | ALDH1A1GAAMAPTHSD17B10NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |