SCHEMBL23729445 — predicted protein targets

Predicted protein targets (top 17)

	gene	UniProt	supporting neighbours	confidence
▸	TSHR	P16473	1/20	0.41

▸	CASP2	P42575	1/20	0.39

▸	NAAA	Q02083	1/20	0.37

▸	MEN1	O00255	2/20	0.36

▸	KMT2A	Q03164	2/20	0.36

▸	EPHX2	P34913	1/20	0.34

▸	GLP1R	P43220	5/20	0.33

▸	SMN1; SMN2	Q16637	2/20	0.33

▸	CA12	O43570	2/20	0.33

▸	CA1	P00915	2/20	0.33

▸	CA2	P00918	2/20	0.33

▸	CA4	P22748	2/20	0.33

▸	CA9	Q16790	2/20	0.33

▸	CA14	Q9ULX7	2/20	0.33

▸	KDM4E	B2RXH2	1/20	0.33

▸	LMNA	P02545	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL21842320	0.84	KDM4E (0.50)	TSHRCASP2NAAAMEN1KMT2A
SCHEMBL25678313	0.84	CASP2 (0.49)	TSHRCASP2NAAAGLP1R
SCHEMBL22623296	0.81	DNM1 (0.48)	TSHRCASP2GLP1R
SCHEMBL24813893	0.80	TSHR (0.40)	TSHRCASP2NAAAMEN1KMT2A
SCHEMBL29299619	0.80	HPGD (0.42)	TSHRCASP2MEN1KMT2AGLP1R
SCHEMBL25791250	0.79	TSHR (0.39)	TSHRCASP2MEN1KMT2AGLP1R
SCHEMBL25029765	0.79	ECE1 (0.43)	TSHRMEN1KMT2ASMN1; SMN2CA12
SCHEMBL21311636	0.79	TSHR (0.49)	TSHRMEN1KMT2ASMN1; SMN2CA12
SCHEMBL23169072	0.79	TSHR (0.49)	TSHRMEN1KMT2ASMN1; SMN2CA12
SCHEMBL20353103	0.79	MEN1 (0.41)	TSHRCASP2NAAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021155321-A2	COMPOUNDS AND USES THEREOF	FOGHORN THERAPEUTICS INC. (US)	2021-08-05	—	—	WO	disclosed