Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25793571 | 0.92 | TSHR (0.43) | TSHRCASP2SAT1NAAAMEN1 | |
| SCHEMBL25678313 | 0.86 | CASP2 (0.49) | TSHRCASP2NAAAFAAHLPAR1 | |
| SCHEMBL25457786 | 0.84 | FAAH (0.41) | TSHRCASP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25791257 | 0.83 | TP53 (0.41) | TSHRCASP2SAT1MEN1KMT2A | |
| SCHEMBL20353103 | 0.81 | MEN1 (0.41) | TSHRCASP2NAAAMEN1KMT2A | |
| SCHEMBL20353102 | 0.81 | MEN1 (0.41) | TSHRCASP2NAAAMEN1KMT2A | |
| SCHEMBL25791250 | 0.81 | TSHR (0.39) | TSHRCASP2MEN1KMT2ACYP2C19 | |
| SCHEMBL25678319 | 0.80 | CASP2 (0.40) | TSHRCASP2NAAAMEN1KMT2A | |
| SCHEMBL23729445 | 0.80 | TSHR (0.41) | TSHRCASP2NAAAMEN1KMT2A | |
| SCHEMBL21842320 | 0.80 | KDM4E (0.50) | TSHRCASP2NAAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272133-A2 | PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS | Stablix, Inc. (US) | 2022-12-29 | — | — | WO | disclosed |