Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.47 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23730027 | 0.91 | GSTO1 (0.49) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21224490 | 0.85 | HDAC4 (0.57) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21224487 | 0.85 | HDAC4 (0.57) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21224245 | 0.84 | HDAC4 (0.54) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21224246 | 0.84 | HDAC4 (0.54) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21241885 | 0.83 | CTSS (0.59) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21224160 | 0.83 | HDAC4 (0.60) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL28522727 | 0.83 | CTSS (0.59) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21224159 | 0.83 | HDAC4 (0.60) | HDAC1HDAC4HDAC3HDAC2HDAC10 | |
| SCHEMBL21225194 | 0.83 | SCN9A (0.54) | HDAC1HDAC4HDAC3HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-11-02 | — | — | US | disclosed |
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348452-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, BRCA1 | HDAC1 378/4885HDAC4 238/4885HDAC3 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.