Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12412458 | 0.89 | SMN1; SMN2 (0.44) | SMN1; SMN2TSHRCASP1CASP7HSD17B10 | |
| SCHEMBL23730060 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2TSHRCASP1CASP7HSD17B10 | |
| SCHEMBL13492963 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1CASP7HSD17B10 | |
| SCHEMBL22794643 | 0.82 | EPHX2 (0.50) | SMN1; SMN2TSHREPHX2FAAHGAA | |
| SCHEMBL23729609 | 0.82 | TSHR (0.59) | SMN1; SMN2TSHRRAB9AALDH1A1L3MBTL1 | |
| SCHEMBL15888692 | 0.81 | TSHR (0.69) | SMN1; SMN2TSHRALDH1A1NAAALMNA | |
| SCHEMBL30648925 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRCASP1CASP7HSD17B10 | |
| SCHEMBL22296982 | 0.81 | NAAA (0.47) | TSHRHSD17B10ALDH1A1NAAAFAAH | |
| SCHEMBL13839061 | 0.80 | FAAH (0.50) | SMN1; SMN2TSHRALDH1A1NAAAFAAH | |
| SCHEMBL23729309 | 0.80 | HPGD (0.49) | SMN1; SMN2TSHRALDH1A1NAAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |