Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23729791 | 0.98 | TSHR (0.44) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26708616 | 0.86 | TSHR (0.44) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26708162 | 0.85 | TSHR (0.42) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26700763 | 0.85 | TSHR (0.42) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL23729612 | 0.85 | FAAH (0.43) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26708614 | 0.85 | FAAH (0.43) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26708617 | 0.85 | TSHR (0.42) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26700903 | 0.84 | FAAH (0.42) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26700902 | 0.84 | FAAH (0.42) | TSHRHPGDSMN1; SMN2CASP2FAAH | |
| SCHEMBL26700900 | 0.81 | HPGD (0.43) | TSHRHPGDSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |