Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23802451 | 0.81 | HPGD (0.55) | HPGDEPHX2CNR1CNR2CYP2D6 | |
| SCHEMBL26700591 | 0.80 | HPGD (0.50) | HPGDEPHX2CNR1CNR2CYP2D6 | |
| SCHEMBL26700589 | 0.80 | HPGD (0.50) | HPGDEPHX2CNR1CNR2CYP2D6 | |
| SCHEMBL23729802 | 0.78 | HPGD (0.51) | HPGDEPHX2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL19685557 | 0.76 | CASP2 (0.59) | EPHX2CNR1CNR2FAAH | |
| SCHEMBL23613251 | 0.75 | HPGD (0.51) | HPGDEPHX2CYP2D6CYP2C19LMNA | |
| SCHEMBL11798160 | 0.75 | HPGD (0.51) | HPGDEPHX2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL20883256 | 0.75 | FAAH (0.64) | HPGDCNR1CNR2FAAHEPHX1 | |
| SCHEMBL21786996 | 0.75 | HPGD (0.51) | HPGDEPHX2CYP2D6CYP2C19LMNA | |
| SCHEMBL1456461 | 0.75 | FAAH (0.64) | HPGDCNR1CNR2FAAHEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |