Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256505 | 0.89 | EPHX2 (0.40) | TSHREPHX2ALDH1A1GAACYP3A4 | |
| SCHEMBL22692705 | 0.88 | TSHR (0.46) | FAAHTSHRALDH1A1GAACYP3A4 | |
| SCHEMBL22857458 | 0.87 | FAAH (0.57) | FAAHLPAR1LPAR2ENPP2DNM1 | |
| SCHEMBL27435739 | 0.83 | FAAH (0.47) | FAAHTSHRLPAR1LPAR2ENPP2 | |
| SCHEMBL26700602 | 0.83 | ALDH1A1 (0.50) | TSHREPHX2ALDH1A1DEGS1GAA | |
| SCHEMBL23730050 | 0.83 | TSHR (0.42) | FAAHTSHRLPAR1LPAR2ENPP2 | |
| SCHEMBL26700570 | 0.83 | ALDH1A1 (0.44) | FAAHTSHRLPAR1LPAR2ENPP2 | |
| SCHEMBL26700567 | 0.83 | ALDH1A1 (0.44) | FAAHTSHRLPAR1LPAR2ENPP2 | |
| SCHEMBL25109864 | 0.82 | GLP1R (0.42) | FAAHEPHX2ALDH1A1DEGS1CYP3A4 | |
| SCHEMBL8165113 | 0.81 | LMNA (0.41) | TSHREPHX2ALDH1A1DEGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |