Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705566 | 0.87 | GSTO1 (0.56) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23705564 | 0.87 | GSTO1 (0.56) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23705601 | 0.87 | GSTO1 (0.56) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23705602 | 0.87 | GSTO1 (0.56) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23730027 | 0.83 | GSTO1 (0.49) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23705731 | 0.81 | HDAC6 (0.58) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23705727 | 0.81 | HDAC6 (0.58) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL30061024 | 0.81 | HDAC4 (0.52) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23729555 | 0.81 | MAPT (0.60) | GSTO1MAPTRAB9ANPC1CASP3 | |
| SCHEMBL23729267 | 0.78 | MRE11 (0.52) | MAPTRAB9ANPC1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |