Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRE11 | P49959 | 10/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23705751 | 0.89 | MRE11 (0.52) | MRE11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23705752 | 0.89 | MRE11 (0.52) | MRE11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL26614504 | 0.85 | CTSS (0.58) | MRE11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL26614511 | 0.85 | CTSS (0.58) | MRE11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23729766 | 0.81 | SMARCA2 (0.46) | MRE11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL26614567 | 0.79 | SMARCA2 (0.60) | MRE11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23730002 | 0.78 | GSTO1 (0.56) | MAPTKDM4EMEN1KMT2AHTT | |
| SCHEMBL23729555 | 0.76 | MAPT (0.60) | MAPTMEN1KMT2AELOVL1NPC1 | |
| SCHEMBL23705549 | 0.76 | HDAC6 (0.52) | MRE11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL23705551 | 0.76 | HDAC6 (0.52) | MRE11MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |