Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18179342 | 0.82 | PGR (0.39) | PGRMEN1KMT2ASMN1; SMN2POLB | |
| SCHEMBL17427493 | 0.81 | CFTR (0.36) | CFTRGOPCPGRALDH1A1S100A4 | |
| SCHEMBL30897426 | 0.81 | CFTR (0.36) | CFTRGOPCPGRALDH1A1S100A4 | |
| SCHEMBL23729942 | 0.81 | TSHR (0.41) | ALDH1A1BCHECES1MAPTTP53 | |
| SCHEMBL16868731 | 0.81 | S100A4 (0.43) | CFTRGOPCPGRALDH1A1S100A4 | |
| SCHEMBL14462993 | 0.79 | S100A4 (0.42) | CFTRGOPCALDH1A1S100A4HSP90AA1 | |
| SCHEMBL31671044 | 0.79 | PGR (0.42) | CFTRGOPCPGRALDH1A1S100A4 | |
| SCHEMBL11844513 | 0.78 | CRBN (0.40) | ALDH1A1ITGA4 | |
| SCHEMBL25201447 | 0.77 | CFTR (0.38) | CFTRGOPCALDH1A1S100A4HSP90AA1 | |
| SCHEMBL29581434 | 0.77 | PGR (0.51) | CFTRGOPCPGRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118993865-A | Chemical resolution method of spiroindenedione compound | 四川大学 | 2024-11-22 | — | — | CN | disclosed |
| US-20240110007-A1 | PREPARATION OF POLY(CROWN ETHER)S | SAUDI ARABIAN OIL COMPANY (SA) | 2024-04-04 | — | — | US | disclosed |
| WO-2021152481-A1 | HYBRID POLYETHER ETHER KETONE POLYMERS | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2021-08-05 | — | — | WO | disclosed |