Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 9/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10414443 | 0.86 | ALOX15 (0.39) | ALOX15TAS1R3TAS1R1PDE4APDE4B | |
| SCHEMBL11611523 | 0.84 | PDE4A (0.43) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL8296526 | 0.83 | CYP2C9 (0.61) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL16950467 | 0.83 | ALOX15 (0.56) | ALOX15TAS1R3TAS1R1PDE4APDE4B | |
| SCHEMBL17833298 | 0.82 | ALOX15 (0.51) | ALOX15TAS1R3TAS1R1PDE4APDE4B | |
| SCHEMBL7644124 | 0.80 | TAS1R3 (0.37) | ALOX15TAS1R3TAS1R1PDE4APDE4B | |
| SCHEMBL7642683 | 0.80 | TAS1R3 (0.38) | ALOX15TAS1R3TAS1R1PDE4APDE4B | |
| SCHEMBL10336472 | 0.80 | TUBB1 (0.50) | ALOX15PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL195793 | 0.80 | ALDH1A1 (0.56) | ALOX15TAS1R3TAS1R1TSHRCYP1A2 | |
| SCHEMBL19462991 | 0.80 | TUBB1 (0.62) | ALOX15PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154661-A1 | 1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-08-05 | — | — | WO | disclosed |