Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 19/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23732808 | 0.88 | EIF2AK3 (0.48) | EIF2AK3METAXL | |
| SCHEMBL23732890 | 0.84 | EIF2AK3 (0.43) | EIF2AK3METAXL | |
| SCHEMBL23732436 | 0.84 | BRD4 (0.56) | EIF2AK3AXL | |
| SCHEMBL28982281 | 0.79 | IGF1R (0.57) | MET | |
| SCHEMBL31327279 | 0.79 | IGF1R (0.57) | MET | |
| SCHEMBL23732425 | 0.79 | IGF1R (0.57) | MET | |
| SCHEMBL18874076 | 0.76 | PIK3CD (0.56) | EIF2AK3METAXL | |
| SCHEMBL23732775 | 0.74 | EGFR (0.48) | EIF2AK3AXL | |
| SCHEMBL17555729 | 0.73 | WNT1 (0.45) | — | |
| SCHEMBL20351797 | 0.72 | EIF2AK3 (0.48) | EIF2AK3METAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155004-A1 | STRAD-BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-08-05 | — | — | WO | disclosed |