SCHEMBL23733015

SCHEMBL23733015

O=C(O)C(=O)N1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PKM P14618 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23733173 0.85 CA12 (0.34) CA12CA1CA9
SCHEMBL432175 0.78 CA12 (0.35) CA12CA1CA9KMT2AALDH1A1
SCHEMBL317539 0.77 CA12 (0.38) CA12CA1CA9ALDH1A1PKM
Hydrochloric Acid SCHEMBL28361628 0.74 CA12 (0.37) CA12CA1CA9ALDH1A1PKM
SCHEMBL5596182 0.74 CA12 (0.33) CA12CA1CA9
SCHEMBL1314059 0.74 CA12 (0.33) CA12CA1CA9KMT2A
SCHEMBL198304 0.73 CA12 (0.34) CA12CA1CA9
SCHEMBL1530917 0.72 KMT2A (0.40) KMT2A
SCHEMBL20305859 0.72 CA12 (0.32) CA12CA1CA9
SCHEMBL9106733 0.71 CA12 (0.33) CA12CA1CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210238155-A1 CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238155-A1 CARBON MONOXIDE PRODRUGS FOR THE TREATMENT OF MEDICAL DISORDERS PYGL, HMOX2, MB CA12 50/4885CA1 356/4885CA9 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.