Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HTR1F | P30939 | 2/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | DRD5 | P21918 | 1/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | HTR1E | P28566 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR1B | P28222 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | GBA1 | P04062 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733250 | 0.83 | HTR1F (0.61) | GRM5MEN1KMT2AHTR1FCHRM5 | |
| SCHEMBL1196838 | 0.82 | MEN1 (0.62) | GRM5MEN1KMT2AHTR1FCHRM5 | |
| SCHEMBL23733275 | 0.82 | MEN1 (0.62) | GRM5MEN1KMT2AHTR1FCHRM5 | |
| SCHEMBL28809348 | 0.82 | MEN1 (0.62) | GRM5MEN1KMT2AHTR1FCHRM5 | |
| SCHEMBL23702725 | 0.82 | HTR1F (0.60) | GRM5MEN1KMT2AHTR1FCHRM5 | |
| SCHEMBL23702723 | 0.81 | HTR1F (0.58) | GRM5MEN1KMT2AHTR1FCHRM5 | |
| SCHEMBL28326270 | 0.79 | GRM5 (0.76) | GRM5KMT2ARAB9ANPC1GBA1 | |
| SCHEMBL31052662 | 0.78 | KMT2A (0.56) | GRM5MEN1KMT2AHTR1FCHRM5 | |
| SCHEMBL5026565 | 0.78 | GRM5 (0.82) | GRM5MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL14319835 | 0.77 | MEN1 (1.00) | GRM5MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152462-A1 | PROCESS FOR PREPARATION OF LASMIDITAN | GLENMARK LIFE SCIENCES LIMITED (IN) | 2021-08-05 | — | — | WO | disclosed |