Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | HTR1F | P30939 | 6/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | DRD5 | P21918 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16321125 | 0.89 | MEN1 (0.78) | MEN1KMT2AGRM5NPC1CYP1A2 | |
| SCHEMBL28808156 | 0.83 | HTR1F (0.56) | MEN1KMT2AHTR1FGRM5NPC1 | |
| SCHEMBL1196838 | 0.82 | MEN1 (0.62) | MEN1KMT2AHTR1FCHRM5DRD5 | |
| SCHEMBL23733271 | 0.82 | GRM5 (0.72) | MEN1KMT2AHTR1FCHRM5DRD5 | |
| SCHEMBL23733275 | 0.82 | MEN1 (0.62) | MEN1KMT2AHTR1FCHRM5DRD5 | |
| SCHEMBL23733250 | 0.80 | HTR1F (0.61) | MEN1KMT2AHTR1FCHRM5DRD5 | |
| SCHEMBL23702725 | 0.79 | HTR1F (0.60) | MEN1KMT2AHTR1FCHRM5DRD5 | |
| SCHEMBL28808130 | 0.79 | CHRNB2 (0.60) | MEN1KMT2AHTR1FGRM5NPC1 | |
| SCHEMBL31052662 | 0.78 | KMT2A (0.56) | MEN1KMT2AHTR1FCHRM5DRD5 | |
| SCHEMBL23702723 | 0.78 | HTR1F (0.58) | MEN1KMT2AHTR1FCHRM5DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045540-B | Preparation method of masmipide | 上海天慈国际药业有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-113045540-A | Preparation method of rasemiptan | 上海天慈国际药业有限公司 | 2021-06-29 | — | — | CN | claimed |
| CN-113045540-B | Preparation method of masmipide | 上海天慈国际药业有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-114728929-A | Pyridine methylene piperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113045540-A | Preparation method of rasemiptan | 上海天慈国际药业有限公司 | 2021-06-29 | — | — | CN | disclosed |