Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23872554 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MLYCDGRNSORT1 | |
| SCHEMBL23613090 | 0.78 | TAS1R3 (0.31) | — | |
| SCHEMBL23872550 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MLYCD | |
| SCHEMBL23872553 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MLYCD | |
| SCHEMBL23872552 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MLYCD | |
| SCHEMBL529993 | 0.74 | TDP1 (0.31) | — | |
| SCHEMBL314769 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL13995976 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL12703373 | 0.69 | TDP1 (0.44) | ALDH1A1 | |
| SCHEMBL14268038 | 0.69 | TDP1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084800-B2 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084800-B2 | Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders | CFD, TFPI, CFH | ALDH1A1 2338/4885MLYCD 922/4885GRN 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.