⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281206 | 1.00 | TRPA1 (0.33) | — | |
| SCHEMBL3281200 | 1.00 | TRPA1 (0.33) | — | |
| SCHEMBL2373374 | 1.00 | — | — | |
| SCHEMBL1602300 | 0.97 | TRPA1 (0.32) | — | |
| SCHEMBL1602298 | 0.97 | TRPA1 (0.32) | — | |
| SCHEMBL3306442 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL10391901 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL12551237 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL3052198 | 0.77 | MEN1 (0.32) | — | |
| SCHEMBL3308456 | 0.77 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150329507-A1 | PROCESSES FOR THE PREPARATION OF ENAMINES | DOW AGROSCIENCES LLC (US) | 2015-11-19 | — | — | US | disclosed |
| EP-2364971-B1 | 2,5-Disubstituted pyridines for the preparation of 2-substituted 5-(1-alkylthio)-alkylpyridines | DOW AGROSCIENCES LLC (US) | 2014-04-30 | — | — | EP | disclosed |
| EP-2364971-B1 | 2,5-Disubstituted pyridines for the preparation of 2-substituted 5-(1-alkylthio)-alkylpyridines | DOW AGROSCIENCES LLC (US) | 2014-04-30 | — | — | EP | disclosed |
| EP-2368879-B1 | 2,5-disubstituted pyridines for the preparation of 2-substituted 5-(1-alkylthio)-alkyl-pyridines | DOW AGROSCIENCES LLC (US) | 2012-11-21 | — | — | EP | disclosed |
| EP-2368879-B1 | 2,5-disubstituted pyridines for the preparation of 2-substituted 5-(1-alkylthio)-alkyl-pyridines | DOW AGROSCIENCES LLC (US) | 2012-11-21 | — | — | EP | disclosed |
| EP-2315750-B1 | IMPROVED PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES | DOW AGROSCIENCES LLC (US) | 2012-11-07 | — | — | EP | disclosed |
| EP-2086936-B1 | Process for the preparation of 2-substituted 5-(1-alkylthio)-alkylpyridines | DOW AGROSCIENCES LLC (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2086936-B1 | Process for the preparation of 2-substituted 5-(1-alkylthio)-alkylpyridines | DOW AGROSCIENCES LLC (US) | 2011-12-21 | — | — | EP | disclosed |
| EP-2368879-A1 | 2,5-disubstituted pyridines for the preparation of 2-substituted 5-(1-alkylthio)-alkyl-pyridines | Dow AgroSciences LLC (US) | 2011-09-28 | — | — | EP | disclosed |
| EP-2368879-A1 | 2,5-disubstituted pyridines for the preparation of 2-substituted 5-(1-alkylthio)-alkyl-pyridines | Dow AgroSciences LLC (US) | 2011-09-28 | — | — | EP | disclosed |
| US-20100004457-A1 | PROCESS FOR THE PREPARATION OF 2-TRIFLUOROMETHYL-5-(1-SUBSTITUTED)ALKYLPYRIDINES | DOW AGROSCIENCES LLC (US) | 2010-01-07 | — | — | US | disclosed |
| EP-2086936-A2 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES | Dow AgroSciences LLC (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008066558-A2 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES | DOW AGROSCIENCES LLC (US) | 2008-06-05 | — | — | WO | disclosed |
| WO-2008066558-A2 | PROCESS FOR THE PREPARATION OF 2-SUBSTITUTED-5-(1-ALKYLTHIO)ALKYLPYRIDINES | DOW AGROSCIENCES LLC (US) | 2008-06-05 | — | — | WO | disclosed |
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | CORTEVA AGRISCIENCE LLC | 2008-06-05 | — | — | US | disclosed |
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | CORTEVA AGRISCIENCE LLC | 2008-06-05 | — | — | US | disclosed |
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | CORTEVA AGRISCIENCE LLC | 2008-06-05 | — | — | US | disclosed |
| US-5466800-A | Process for the preparation of 2,5-disubstituted pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-11-14 | — | — | US | disclosed |
| EP-0584491-B1 | Process for the production of 2,5-disubstituted pyridines | BAYER AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0584491-A1 | Process for the production of 2,5-disubstituted pyridines | BAYER AG (DE) | 1994-03-02 | — | — | EP | disclosed |