Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373370 | 1.00 | — | — | |
| SCHEMBL3281200 | 1.00 | TRPA1 (0.33) | TRPA1 | |
| SCHEMBL2373374 | 1.00 | — | — | |
| SCHEMBL1602300 | 0.97 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL1602298 | 0.97 | TRPA1 (0.32) | TRPA1 | |
| SCHEMBL3306442 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL10391901 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL12551237 | 0.79 | MEN1 (0.32) | — | |
| SCHEMBL3052198 | 0.77 | MEN1 (0.32) | — | |
| SCHEMBL3308456 | 0.77 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705154-B2 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | CORTEVA AGRISCIENCE LLC | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132705-A1 | Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines | AGPS, TPMT, PFAS | TRPA1 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.