SCHEMBL23733879

SCHEMBL23733879

Fc1ccc(-c2nc(-c3ccc(F)cc3)nc(-c3ccc(-c4ccc5ccc(-c6ccccc6)cc5c4)cc3)n2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.52
ESR2 Q92731 3/20 0.52
NR3C1 P04150 1/20 0.49
DPP4 P27487 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
HPGD P15428 1/20 0.46
ABCG2 Q9UNQ0 1/20 0.45
CYP1A2 P05177 2/20 0.45
KDM4E B2RXH2 2/20 0.45
TP53 P04637 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSD17B10 Q99714 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
BACE1 P56817 1/20 0.43
CYP2A6 P11509 1/20 0.42
FLT3 P36888 1/20 0.42
NTSR1 P30989 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16716570 1.00 ESR1 (0.52) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL23733873 0.96 ESR1 (0.49) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL23733841 0.95 MEN1 (0.51) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL23733823 0.94 ESR1 (0.50) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL23733834 0.94 ESR1 (0.50) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL23733837 0.94 ESR1 (0.50) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL23733870 0.94 ESR1 (0.50) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL16716514 0.93 ESR1 (0.44) ESR1ESR2NR3C1DPP4MEN1
SCHEMBL23733833 0.91 CYP1A2 (0.54) ESR1ESR2NR3C1MEN1KMT2A
SCHEMBL23733831 0.91 CYP1A2 (0.54) ESR1ESR2NR3C1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-12-12 US disclosed
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-24 US disclosed
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-25 US disclosed
US-11088331-B2 2021-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11563183-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 ESR1 502/4885ESR2 1573/4885NR3C1 1173/4885
US-11844273-B2 Heterocyclic compound and organic light-emitting device including the same DDT, PPOX, LEF1 ESR1 502/4885ESR2 1573/4885NR3C1 1173/4885
US-11088331-B2 DDT, PPOX, DBF4 ESR1 588/4885ESR2 1438/4885NR3C1 804/4885
US-20210367158-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME DDT, PPOX, LEF1 ESR1 502/4885ESR2 1573/4885NR3C1 1173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.