Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733923 | 0.88 | CYP2C19 (0.42) | CYP2C19EPHX2PLA2G4BCES2CYP4F2 | |
| SCHEMBL22922026 | 0.88 | CES2 (0.41) | CYP2C19EPHX2PLA2G4BCES2GMNN | |
| SCHEMBL22921751 | 0.86 | EPHX2 (0.39) | CYP2C19EPHX2PLA2G4BCES2GMNN | |
| SCHEMBL17833869 | 0.80 | PTGS1 (0.36) | CYP2C19EPHX2THRBBLMHSD17B10 | |
| SCHEMBL29313400 | 0.79 | CES2 (0.43) | CYP2C19EPHX2PLA2G4BCES2GMNN | |
| SCHEMBL22771248 | 0.78 | HSD17B10 (0.35) | CYP2C19EPHX2TP53THRBBLM | |
| SCHEMBL23733921 | 0.78 | CYP2C19 (0.36) | CYP2C19EPHX2CES2CYP4F2CYP4A11 | |
| SCHEMBL18660231 | 0.75 | CES2 (0.50) | CYP2C19EPHX2PLA2G4BCES2THRB | |
| SCHEMBL7713583 | 0.75 | CES2 (0.50) | CYP2C19EPHX2PLA2G4BCES2THRB | |
| SCHEMBL30372910 | 0.75 | CYP2C19 (0.38) | CYP2C19EPHX2CES2CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084773-B1 | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease | ESPERVITA THERAPEUTICS, INC. (US) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084773-B1 | Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and their use for the prevention or treatment of disease | CPT1A, PPARG, PC | CYP2C19 1045/4885EPHX2 1239/4885PLA2G4B 1712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.