Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CTH | P32929 | 1/20 | 0.41 |
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18660231 | 1.00 | CES2 (0.50) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL22922164 | 0.97 | CES2 (0.48) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL10001230 | 0.97 | CES2 (0.46) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL23405393 | 0.95 | CES2 (0.46) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL20535086 | 0.95 | CES2 (0.46) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL22922080 | 0.94 | CES2 (0.44) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL23405410 | 0.94 | CES2 (0.44) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL22609488 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHRTHRBPLA2G4BLMNA | |
| SCHEMBL7760402 | 0.90 | GPR84 (0.48) | CES2CYP2C19EPHX2ALDH1A1CYP4F2 | |
| SCHEMBL2600800 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHRTHRBPLA2G4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365172-B1 | SELF-REINFORCED BIOABSORBABLE DEVICE COMPRISED OF FUSED OR SINTERED FIBERS MADE FROM BIOABSORBABLE POLYMER COMPRISING SPECIFIED POLYESTERAMIDE | BIOAMIDE, INC. | 2002-04-02 | — | — | US | disclosed |
| US-6120788-A | Bioabsorbable triglycolic acid poly(ester-amide)s | BIOAMIDE, INC. (US) | 2000-09-19 | — | — | US | disclosed |