Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 20/20 | 0.87 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21219312 | 0.99 | OPRK1 (0.88) | OPRK1OPRM1 | |
| SCHEMBL20030781 | 0.99 | OPRK1 (0.88) | OPRK1OPRM1 | |
| SCHEMBL28455860 | 0.98 | OPRK1 (0.85) | OPRK1OPRM1 | |
| SCHEMBL20030352 | 0.97 | OPRK1 (0.90) | OPRK1OPRM1 | |
| SCHEMBL21219361 | 0.97 | OPRK1 (0.90) | OPRK1OPRM1 | |
| SCHEMBL21286619 | 0.94 | OPRK1 (0.98) | OPRK1OPRM1 | |
| SCHEMBL23841287 | 0.94 | OPRK1 (0.98) | OPRK1OPRM1 | |
| Difelikefalin SCHEMBL25386632 | 0.93 | OPRK1 (1.00) | OPRK1OPRM1 | |
| Difelikefalin SCHEMBL19040667 | 0.93 | OPRK1 (1.00) | OPRK1OPRM1 | |
| Difelikefalin SCHEMBL20669281 | 0.93 | OPRK1 (1.00) | OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084847-B2 | Polyamide compound and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084847-B2 | Polyamide compound and use thereof | OPRK1, OPRM1, OPRD1 | OPRK1 1/4885OPRM1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.