Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 11/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.48 |
| ▸ | TUBB | P07437 | 6/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10789120 | 0.82 | TSHR (0.56) | HTTTSHRAPOBEC3AAPOBEC3GTUBB1 | |
| SCHEMBL4625442 | 0.81 | TUBB1 (0.58) | HTTTSHRAPOBEC3AAPOBEC3GTUBB1 | |
| 3,4,5-Trimethoxybenzamide SCHEMBL1326890 | 0.77 | TSHR (0.76) | HTTTSHRAPOBEC3AAPOBEC3GTUBB1 | |
| SCHEMBL23734449 | 0.76 | TUBB1 (0.55) | HTTTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL907576 | 0.76 | TPMT (0.56) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| 3,4,5-Trimethoxybenzamide SCHEMBL4381076 | 0.76 | TSHR (0.73) | HTTTSHRAPOBEC3AAPOBEC3GTUBB1 | |
| SCHEMBL31679677 | 0.74 | TUBB1 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6160353 | 0.74 | TUBB1 (0.54) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4819729 | 0.73 | TUBB4A (0.75) | TSHRTUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL20006949 | 0.73 | TUBB1 (0.56) | HTTTUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084811-B2 | Compounds for treatment of cancer | Oncternal Therapeutics, Inc. (US) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084811-B2 | Compounds for treatment of cancer | KLK3, BRDT, ACP3 | HTT 4461/4885TSHR 4440/4885APOBEC3A 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.