Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.75 |
| ▸ | TUBB | P07437 | 5/20 | 0.75 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.75 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.75 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.75 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.75 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.75 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.75 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.75 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.75 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.75 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.75 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.75 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.75 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27888195 | 0.98 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6455798 | 0.90 | KMT2A (0.65) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4818395 | 0.90 | TUBB4A (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4824662 | 0.88 | CYP1A2 (0.81) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2450750 | 0.88 | TUBB4A (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9933825 | 0.88 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31369135 | 0.88 | CYP1A2 (0.81) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6462743 | 0.88 | TUBB4A (0.62) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9189645 | 0.87 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4625442 | 0.86 | TUBB1 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850170-A | Acridine-10 (9H) - (3, 4, 5-trimethoxyphenyl) ketone compound and preparation method and application thereof | 英维沃化工科技(广州)有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-107690429-A | composition for the treatment and/or prevention of cell or tissue necrosis, specifically targeting cathepsin C and/or CE L a1 and/or CE L A3A and/or enzymes structurally related thereto | ELA制药有限公司 | 2018-02-13 | — | — | CN | claimed |
| CN-106279027-A | (1 aryl 1H pyrazoles 4 base) (3,4,5 trimethoxyphenyl) ketone, ketoxime compounds and application thereof | 沈阳药科大学 | 2017-01-04 | — | — | CN | claimed |
| CN-103442566-B | The compound of Therapeutic cancer | GTX, INC. (US) | 2015-12-09 | — | — | CN | claimed |
| CN-102883607-B | Compounds for the treatment of cancer | GTX INC | 2015-07-22 | — | — | CN | claimed |
| CN-104610230-A | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION | 2015-05-13 | — | — | CN | claimed |
| CN-102137592-B | Compounds for the treatment of cancer | UNIV TENNESSEE RES FOUNDATION (US) | 2015-01-28 | — | — | CN | claimed |
| CN-102391260-B | 3-ketone-6-substituted-benzofuran compound and preparation method and application thereof | UNIV SHANGHAI JIAOTONG | 2014-12-10 | — | — | CN | claimed |
| CN-102883607-A | Compounds for the treatment of cancer | GTX INC (US) | 2013-01-16 | — | — | CN | claimed |
| US-20250250254-A1 | DEUTERATED HETEROCYCLIC KETONE COMPOUND AND USE THEREOF | HINOVA PHARMACEUTICALS INC. (CN) | 2025-08-07 | — | — | US | disclosed |
| EP-4509501-A1 | DEUTERATED HETEROCYCLIC KETONE COMPOUND AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2025-02-19 | — | — | EP | disclosed |
| CN-117447436-A | Spiropyran derivative, color-changing glass paint and preparation method and application thereof | 广州市科涵实业有限责任公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-117396505-A | Methods of treating inflammation | 维鲁公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-115850170-A | Acridine-10 (9H) - (3, 4, 5-trimethoxyphenyl) ketone compound and preparation method and application thereof | 英维沃化工科技(广州)有限公司 | 2023-03-28 | — | — | CN | disclosed |
| EP-1603864-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2005-12-14 | — | — | EP | disclosed |
| US-20050107339-A1 | Diphenylethylene compounds and uses thereof | CELGENE CORPORATION | 2005-05-19 | — | — | US | disclosed |
| US-20050014727-A1 | Diphenylethylene compounds and uses thereof | CELGENE CORPORATION | 2005-01-20 | — | — | US | disclosed |
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |
| US-20040034239-A1 | Inhibitors of nadh:ubiquinone oxidoreductase | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-19 | — | — | US | disclosed |
| WO-2002020008-A1 | INHIBITORS OF NADH:UBIQUINONE OXIDOREDUCTASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107339-A1 | Diphenylethylene compounds and uses thereof | VHL, TNF, PTGES | TUBB4A 2850/4885TUBB 3365/4885TUBA3C 2433/4885 |
| US-20250250254-A1 | DEUTERATED HETEROCYCLIC KETONE COMPOUND AND USE THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TUBB1, TUBA1C | TUBB4A 34/4885TUBB 5/4885TUBA3C 4/4885 |
| US-20040034239-A1 | Inhibitors of nadh:ubiquinone oxidoreductase | NQO1, NDUFV1, NDUFV2 | TUBB4A 1162/4885TUBB 854/4885TUBA3C 2907/4885 |
| US-20050014727-A1 | Diphenylethylene compounds and uses thereof | VHL, TNF, PTGES | TUBB4A 2850/4885TUBB 3365/4885TUBA3C 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.