Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | BCR | P11274 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 3/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CELA1 | Q9UNI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470717 | 0.90 | LMNA (0.67) | LMNAGAAGFERMAPTTDP1 | |
| SCHEMBL8523753 | 0.90 | CYP3A4 (0.66) | LMNAGAAGFERMAPTTDP1 | |
| SCHEMBL28868218 | 0.89 | HSD17B10 (0.62) | LMNAGAAGFERMAPTTDP1 | |
| SCHEMBL6853303 | 0.89 | HSD17B10 (0.66) | LMNAGAAGFERMAPTTDP1 | |
| SCHEMBL4960001 | 0.87 | LMNA (0.71) | LMNAGAAGFERMAPTTDP1 | |
| SCHEMBL4607313 | 0.86 | LMNA (0.71) | LMNAGAAGFERMAPTTDP1 | |
| SCHEMBL9544647 | 0.83 | HSD17B10 (0.68) | LMNAGAAMAPTTDP1MEN1 | |
| 4-Acetoxyphenol SCHEMBL203149 | 0.83 | LMNA (0.67) | LMNAGAAGFERMAPTMEN1 | |
| SCHEMBL13680438 | 0.83 | LMNA (0.67) | LMNAGAAGFERMAPTTDP1 | |
| SCHEMBL11043958 | 0.82 | HSD17B10 (0.63) | LMNAGAAGFERMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3580258-B1 | OLIGOMERIC POLYOL COMPOSITIONS | PRESIDIUM USA INC (US) | 2021-08-11 | — | — | EP | disclosed |