Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23735017 | 0.96 | KDM4E (0.37) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL23735024 | 0.88 | KDM4E (0.44) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL23735090 | 0.88 | QDPR (0.39) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL23735012 | 0.87 | DRD2 (0.40) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL23735066 | 0.86 | PPARG (0.37) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL23735061 | 0.86 | DRD2 (0.43) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL23735076 | 0.86 | DRD2 (0.43) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL23735038 | 0.86 | PPARG (0.43) | PPARGPPARAKDM4ESIGMAR1 | |
| SCHEMBL23735106 | 0.85 | KCNA3 (0.41) | PPARGPPARAKDM4EDRD2DRD4 | |
| SCHEMBL19989699 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519387-B1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG A ST CO LTD (KR) | 2021-08-11 | — | — | EP | disclosed |