Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23735076 | 0.93 | DRD2 (0.43) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23734849 | 0.91 | DRD2 (0.42) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735061 | 0.91 | DRD2 (0.43) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735090 | 0.90 | QDPR (0.39) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735024 | 0.90 | KDM4E (0.44) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23734937 | 0.89 | DRD2 (0.42) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735041 | 0.89 | DRD2 (0.41) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735066 | 0.88 | PPARG (0.37) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735005 | 0.87 | PPARG (0.36) | DRD2DRD4DRD3PPARGPPARA | |
| SCHEMBL23735106 | 0.87 | KCNA3 (0.41) | DRD2DRD4PPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519387-B1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG A ST CO LTD (KR) | 2021-08-11 | — | — | EP | disclosed |