Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 9/20 | 0.34 |
| ▸ | HTR2B | P41595 | 9/20 | 0.34 |
| ▸ | HTR2A | P28223 | 7/20 | 0.34 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.32 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.32 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.32 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19684588 | 0.75 | PNMT (0.41) | HTR2CHTR2BHTR2APNMTASIC3 | |
| SCHEMBL19684606 | 0.73 | PNMT (0.39) | HTR2CHTR2BHTR2APNMTASIC3 | |
| SCHEMBL19711570 | 0.73 | PNMT (0.39) | HTR2CHTR2BHTR2APNMTASIC3 | |
| SCHEMBL22658197 | 0.70 | KDM4E (0.30) | — | |
| SCHEMBL29433292 | 0.70 | KDM4E (0.30) | — | |
| SCHEMBL19443102 | 0.67 | PNMT (0.51) | CD44HTR2CHTR2BHTR2ADRD2 | |
| SCHEMBL19684653 | 0.65 | HRH3 (0.38) | PNMT | |
| SCHEMBL719964 | 0.64 | ADCY6 (0.56) | CD44HTR2CHTR2BHTR2AADCY6 | |
| SCHEMBL19684597 | 0.64 | ASIC3 (0.40) | HTR2CHTR2BHTR2APNMTASIC3 | |
| SCHEMBL19406903 | 0.64 | PNMT (0.39) | HTR2CHTR2BHTR2APNMTASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464249-B1 | SUBSTITUTED CARBONUCLEOSIDE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER (US) | 2021-08-11 | — | — | EP | disclosed |