SCHEMBL23735560

SCHEMBL23735560

CC(=O)NCCCCNC(=O)C(=O)NCCCCNC=O

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.60
MAPK1 P28482 1/20 0.60
HIF1A Q16665 1/20 0.60
PAOX Q6QHF9 3/20 0.53
ADRA1A P35348 1/20 0.48
ADH1B P00325 3/20 0.46
ADH1A P07327 3/20 0.46
ADH7 P40394 3/20 0.46
ADH1C P00326 2/20 0.46
EPHX1 P07099 1/20 0.45
ADH4 P08319 1/20 0.45
TSHR P16473 1/20 0.40
ALDH1A1 P00352 2/20 0.39
EPHX2 P34913 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
CBLB Q13191 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27383468 0.94 KDM4E (0.68) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL22811174 0.91 KDM4E (0.73) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL14910879 0.91 KDM4E (0.65) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL23442125 0.91 KDM4E (0.73) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL23735558 0.87 KDM4E (0.79) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL23735383 0.82 KDM4E (0.54) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL404097 0.82
SCHEMBL23735537 0.81 KDM4E (0.57) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL22710264 0.80 ADH1B (0.43) KDM4EMAPK1HIF1APAOXADRA1A
SCHEMBL23735542 0.80 EPHX1 (0.55) KDM4EMAPK1HIF1AADH1BADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3157978-B1 STRICTLY SEGMENTED THERMOPLASTIC ELASTOMERS AS BIODEGRADABLE BIOMATERIALS SYMO CHEM B V (NL) 2021-08-11 EP disclosed