Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 5/20 | 0.45 |
| ▸ | BACE1 | P56817 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23736282 | 0.94 | GAA (0.47) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL23736230 | 0.89 | GAA (0.50) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL15727180 | 0.89 | CTSD (0.55) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL17884315 | 0.84 | CTSD (0.49) | GAACTSDBACE1 | |
| SCHEMBL23736034 | 0.83 | GAA (0.48) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL23736117 | 0.82 | GAA (0.47) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL15727315 | 0.82 | CTSD (0.53) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL15727314 | 0.78 | CTSD (0.55) | GAACTSDBACE1 | |
| SCHEMBL15750409 | 0.78 | BACE1 (0.47) | GAACTSDBACE1NFKB1NFKB2 | |
| SCHEMBL27419818 | 0.75 | GAA (0.48) | GAACTSDBACE1NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922829-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-08-11 | — | — | EP | disclosed |