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Sugi Predict / Compounds / SCHEMBL2373652

SCHEMBL2373652

SCHEMBL2373652

Cc1cc(C)c(-c2ccnc3c2ccc2ccc4c(-c5c(C)cc(C)cc5C)ccnc4c23)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 5/20 0.42
▸ CCR8 P51685 5/20 0.42
▸ CCR5 P51681 4/20 0.42
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ CRHR1 P34998 4/20 0.35
▸ PTGDR2 Q9Y5Y4 2/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ PTGS1 P23219 1/20 0.34
▸ SLC6A4 P31645 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ PTGS2 P35354 1/20 0.34
▸ LMNA P02545 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ MAPT P10636 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HTT P42858 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ PSMD14 O00487 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14481835 0.89 CCR1 (0.38) CCR1CCR8CCR5L3MBTL1CRHR1
SCHEMBL28073836 0.71 ALDH1A1 (0.55) L3MBTL1CRHR1ALDH1A1HPGDMAPT
SCHEMBL5466033 0.70 PSMB5 (0.42) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL14451019 0.69 COMT (0.64) L3MBTL1LMNAALDH1A1MAPTMAPK1
SCHEMBL12315220 0.68 CCR1 (0.48) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL26343428 0.68 CCR1 (0.34) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL26563803 0.68 CCR1 (0.47) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL28718102 0.68 CCR1 (0.54) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL30413421 0.68 CCR1 (0.54) CCR1CCR8CCR5L3MBTL1LMNA
SCHEMBL14494236 0.68 NUDT1 (0.54) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9627632-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-04-18 — — US disclosed
US-9627632-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-04-18 — — US disclosed
US-9627632-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-04-18 — — US disclosed
EP-2550691-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2013-01-30 — — EP disclosed
US-20130009118-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-10 — — US disclosed
US-20130009118-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-10 — — US disclosed
US-20130009118-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-10 — — US disclosed
WO-2011116857-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-09-29 — — WO disclosed
WO-2011116857-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130009118-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SOD1, L1CAM, EPCAM CCR1 2911/4885CCR8 3022/4885CCR5 1626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.