Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 4/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL236793 | 0.77 | TTR (0.32) | — | |
| SCHEMBL2791417 | 0.73 | MAOB (0.36) | CTSLCTSBALDH1A1HDAC8 | |
| SCHEMBL235262 | 0.72 | CES2 (0.33) | CES2GAACTSLCYP2C9TSHR | |
| SCHEMBL238446 | 0.71 | MEN1 (0.39) | ALDH1A1 | |
| SCHEMBL234054 | 0.70 | — | — | |
| SCHEMBL27741685 | 0.69 | TACR1 (0.38) | TACR1KDM4ERAPGEF3RAPGEF4GPBAR1 | |
| SCHEMBL27765351 | 0.66 | PNMT (0.41) | CES2GAATACR1KDM4EGPBAR1 | |
| SCHEMBL4307602 | 0.64 | CES2 (0.50) | CES2GAATACR1CYP2C9TSHR | |
| SCHEMBL11623513 | 0.63 | CES2 (0.52) | CES2CTSLALDH1A1 | |
| SCHEMBL4306951 | 0.63 | CES2 (0.59) | CES2GAATACR1GPBAR1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |