Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237620 | 0.78 | CTSS (0.32) | GAACTSLAR | |
| SCHEMBL237397 | 0.76 | MEN1 (0.35) | AR | |
| SCHEMBL237367 | 0.72 | CES2 (0.36) | CES2CYP2C9TSHRGAACTSL | |
| SCHEMBL4307602 | 0.60 | CES2 (0.50) | CES2CYP2C9TSHRGAARAPGEF3 | |
| SCHEMBL28057001 | 0.60 | CYP19A1 (0.41) | CES2RAPGEF3RAPGEF4AR | |
| SCHEMBL23621087 | 0.60 | CES2 (0.48) | CES2GAARAPGEF3RAPGEF4 | |
| SCHEMBL21609834 | 0.59 | CES2 (0.48) | CES2GAARAPGEF3RAPGEF4 | |
| SCHEMBL30056963 | 0.59 | CES2 (0.48) | CES2GAARAPGEF3RAPGEF4 | |
| SCHEMBL28510841 | 0.58 | CES2 (0.47) | CES2GAARAPGEF3RAPGEF4GPBAR1 | |
| SCHEMBL21610861 | 0.58 | CYP19A1 (0.35) | CES2RAPGEF3RAPGEF4GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |