SCHEMBL2373683

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31439555	0.84	POLB (0.46)	HRH4ALDH1A1MAPTPOLBLMNA
	SCHEMBL16700915	0.84	POLB (0.46)	HRH4ALDH1A1MAPTPOLBLMNA
	SCHEMBL14994818	0.80	KDM4E (0.37)	HRH4ALDH1A1MAPTPOLBLMNA
	SCHEMBL9070294	0.79	ALDH1A1 (0.59)	ALDH1A1MAPTPOLBTLR8KDM4E
	SCHEMBL7519140	0.79	ALDH1A1 (0.44)	ALDH1A1MAPTPOLBHTTTLR8
	SCHEMBL11470307	0.78	ALDH1A1 (0.63)	ALDH1A1MAPTPOLBLMNATLR8
	Hydrochloric Acid SCHEMBL9781178	0.78	ALDH1A1 (0.57)	ALDH1A1MAPTPOLBTLR8KDM4E
	SCHEMBL1341730	0.78	CYP3A4 (0.48)	ALDH1A1POLBSMN1; SMN2TLR8EP300
	SCHEMBL155113	0.77	ALDH1A1 (0.61)	ALDH1A1MAPTPOLBHTTAPP
	SCHEMBL25298194	0.77	SLC6A4 (0.40)	HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.