Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48359 | 0.86 | GPR35 (0.55) | GPR35TSHRCYP1A2MAPTCYP2C9 | |
| SCHEMBL3206927 | 0.86 | GPR35 (0.55) | GPR35TSHRCYP1A2MAPTCYP2C9 | |
| SCHEMBL211181 | 0.86 | ALDH1A1 (0.58) | GPR35CYP1A2MAPTCYP2C9TDP1 | |
| SCHEMBL48361 | 0.85 | GPR35 (0.53) | GPR35TSHRCYP1A2MAPTCYP2C9 | |
| SCHEMBL48360 | 0.85 | GPR35 (0.53) | GPR35TSHRCYP1A2MAPTCYP2C9 | |
| SCHEMBL17005575 | 0.83 | TSHR (0.51) | GPR35TSHRMAPTTDP1ALDH1A1 | |
| SCHEMBL1421203 | 0.83 | TDP1 (0.57) | CYP1A2MAPTCYP2C9TDP1ALDH1A1 | |
| SCHEMBL1652615 | 0.83 | GPR35 (0.51) | GPR35TSHRCYP1A2MAPTCYP2C9 | |
| SCHEMBL1653791 | 0.83 | GPR35 (0.47) | GPR35TSHRCYP1A2MAPTCYP2C9 | |
| SCHEMBL25331485 | 0.82 | TSHR (0.50) | GPR35TSHRMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021137611-A1 | IMMUNE CELLS HAVING NANOSTRUCTURE ATTACHED THERETO | (주)테라베스트 | 2021-07-08 | — | — | WO | disclosed |
| CN-111479806-A | D-amino acid oxidase inhibitors and therapeutic uses thereof | 心悦生医股份有限公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-3676267-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | Dana Farber Cancer Institute, Inc. (US) | 2020-07-08 | — | — | EP | disclosed |
| WO-2019046775-A1 | INHIBITORS OF EGFR AND/OR HER2 AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2019-03-07 | — | — | WO | disclosed |
| EP-2365962-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | Massachusetts Institute of Technology (US) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |
| EP-0830340-A1 | FACE-TO-FACE/FACE-TO-EDGE INTERACTIVE CHIRAL SELECTORS AND RELATED APPARATUSES | Research Corporation Technologies, Inc (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996039377-A1 | FACE-TO-FACE/FACE-TO-EDGE INTERACTIVE CHIRAL SELECTORS AND RELATED APPARATUSES | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1996-12-12 | — | — | WO | disclosed |