Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.32 |
| ▸ | HTR3B | O95264 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23740098 | 0.92 | ADAM17 (0.35) | ACKR3LMNAPOLBMAPTGAA | |
| SCHEMBL23739968 | 0.86 | IDO1 (0.37) | ACKR3LMNAPOLBMAPTTHRB | |
| SCHEMBL23739656 | 0.86 | IDO1 (0.38) | ACKR3LMNAPOLBTHRBGAA | |
| SCHEMBL23739714 | 0.85 | ADAM17 (0.39) | — | |
| SCHEMBL23739667 | 0.84 | POLB (0.35) | LMNAPOLBMAPTTHRBGAA | |
| SCHEMBL23739649 | 0.84 | ACKR3 (0.37) | ACKR3AGTR1AGTR2P2RY12MAPT | |
| SCHEMBL23740057 | 0.82 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL23739890 | 0.81 | POLB (0.35) | LMNAPOLBMAPTTHRBGAA | |
| SCHEMBL24572202 | 0.81 | POLB (0.35) | LMNAPOLBMAPTTHRBGAA | |
| SCHEMBL23739521 | 0.80 | POLB (0.35) | LMNAPOLBMAPTTHRBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862348-A1 | ISOINDOLINE COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-08-11 | — | — | EP | disclosed |