Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | NQO2 | P16083 | 11/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755315 | 0.81 | RAB9A (0.68) | MAPTRAB9ANPC1THRBBLM | |
| SCHEMBL11208368 | 0.80 | MAPT (0.67) | MAPTRAB9ANPC1THRBBLM | |
| SCHEMBL7755602 | 0.80 | NQO2 (0.67) | MAPTRAB9ANPC1THRBBLM | |
| SCHEMBL1513023 | 0.77 | NQO2 (1.00) | MAPTRAB9ANPC1THRBBLM | |
| Hydrogen Sulfide SCHEMBL28130030 | 0.76 | NQO2 (0.96) | MAPTRAB9ANPC1THRBBLM | |
| Hydrochloric Acid SCHEMBL27564424 | 0.76 | NQO2 (0.96) | MAPTRAB9ANPC1THRBBLM | |
| Hydrochloric Acid SCHEMBL28752582 | 0.76 | NQO2 (0.96) | MAPTRAB9ANPC1THRBBLM | |
| Ammonia Solution, Strong SCHEMBL27633219 | 0.76 | NQO2 (0.96) | MAPTRAB9ANPC1THRBBLM | |
| SCHEMBL1856937 | 0.75 | MAPT (0.59) | MAPTRAB9ANPC1THRBBLM | |
| SCHEMBL29670010 | 0.75 | MAPT (0.59) | MAPTRAB9ANPC1THRBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9034857-B2 | Methods for reducing superoxide anions in eukaryotic organisms | HEALTH RESEARCH, INC. (US) | 2015-05-19 | — | — | US | disclosed |
| US-20130150336-A1 | Methods For Reducing Superoxide Anions in Eukaryotic Organisms | STC.UNM (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011119798-A1 | METHODS FOR REDUCING SUPEROXIDE ANIONS IN EUKARYOTIC ORGANISMS | HEALTH RESEARCH, INC. (US) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150336-A1 | Methods For Reducing Superoxide Anions in Eukaryotic Organisms | TXN2, TXNRD2, PRDX5 | MAPT 3511/4885RAB9A 3105/4885NPC1 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.