SCHEMBL11208368

SCHEMBL11208368

COc1ccc2nc(C)c(C)nc2c1N

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.67
NPC1 O15118 2/20 0.67
RAB9A P51151 2/20 0.67
KDM4E B2RXH2 1/20 0.67
GAA P10253 1/20 0.67
THRB P10828 1/20 0.67
MAPK1 P28482 1/20 0.67
BLM P54132 1/20 0.67
ATM Q13315 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
NQO2 P16083 3/20 0.41
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
DHFR P00374 3/20 0.39
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
G6PD P11413 1/20 0.38
PKM P14618 1/20 0.38
DCPS Q96C86 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2373965 0.80 MAPT (1.00) MAPTNPC1RAB9AKDM4EGAA
SCHEMBL28033039 0.79 PDE3B (0.45) MAPTNPC1RAB9AKDM4EGAA
SCHEMBL12964209 0.76 MAPT (0.70) MAPTNPC1RAB9AKDM4EGAA
SCHEMBL18083015 0.76 MAPT (1.00) MAPTNPC1RAB9AKDM4EGAA
SCHEMBL11713713 0.75 NQO2 (0.60) MAPTNPC1RAB9AKDM4EL3MBTL1
SCHEMBL18387578 0.73 NQO2 (0.69) MAPTNPC1RAB9AKDM4ETHRB
SCHEMBL11202171 0.72 MAPT (0.62) MAPTNPC1RAB9AKDM4EGAA
SCHEMBL8395246 0.72 MEN1 (0.57) MAPTNPC1RAB9AKDM4EGAA
SCHEMBL3520256 0.71 ALDH1A1 (0.49) MAPTRAB9AKDM4EL3MBTL1ALDH1A1
SCHEMBL1710455 0.70 ALDH1A1 (0.50) MAPTNPC1RAB9AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed
US-4186008-A STRONG ACID, WATER-SOLUBLE IODIDE, NON-QUATERNIZED QUINOXALINE OR PYRAZINE, ANIT-OXIDANT, QUATERNARY AMMONIUM SALT OF AMINE SALT CIBA-GEIGY AKTIENGESELLSCHAFT (CH) 1980-01-29 US disclosed
US-4046566-A PROCESS FOR THE PRODUCTION OF MASKED POSITIVE COLOR IMAGES BY THE SILVER DYE BLEACH PROCESS USING SILVER COMPLEX DIFFUSION CIBA-GEIGY AG (CH) 1977-09-06 US disclosed
US-4014698-A ACIDS, IODIDE COMPOUNDS, OXIDIZERS, DIAZINE COMPOUND CIBA-GEIGY AG (CH) 1977-03-29 US disclosed