Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 13/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 11/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23739867 | 0.94 | ADRA1D (0.39) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23739826 | 0.91 | ADRA1D (0.37) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23739757 | 0.91 | ADRA1D (0.36) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23739516 | 0.91 | ADRA1A (0.36) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23740086 | 0.91 | ADRA1D (0.37) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23739797 | 0.89 | OPRM1 (0.37) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23739993 | 0.89 | ADRA1A (0.37) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23739630 | 0.89 | PDE4B (0.43) | ADRA1AADRA1DADRA1B | |
| SCHEMBL23739514 | 0.88 | ADRA1A (0.36) | ADRA1AADRA1DADRA1BOPRM1 | |
| SCHEMBL23739520 | 0.88 | ADRA1A (0.37) | ADRA1AADRA1DADRA1BOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3862348-A1 | ISOINDOLINE COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-08-11 | — | — | EP | disclosed |