SCHEMBL23740285

SCHEMBL23740285

CC(C)(C)CC(C)(C(=O)OCC(O)COC(=O)CS)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.30
DUSP3 P51452 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
LMNA P02545 1/20 0.30
LPAR6 P43657 1/20 0.30
LPAR1 Q92633 1/20 0.30
LPAR4 Q99677 1/20 0.30
LPAR5 Q9H1C0 1/20 0.30
LPAR2 Q9HBW0 1/20 0.30
LPAR3 Q9UBY5 1/20 0.30
ENPP2 Q13822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17166283 0.84 PRKCA (0.31)
SCHEMBL26031785 0.83 PRKCA (0.30)
SCHEMBL14219213 0.82 KDM4E (0.39) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL9057488 0.82 PRKCA (0.32) ADRB2ADRB1ADRB3
SCHEMBL17676405 0.79 LMNA (0.31) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL23986070 0.79 KDM4E (0.32) KDM4EDUSP3MEN1KMT2ALMNA
SCHEMBL17695486 0.79 TSHR (0.45) TSHRHSD17B10
SCHEMBL13114673 0.79 TSHR (0.45) TSHR
SCHEMBL12374351 0.78 MAPK1 (0.38)
SCHEMBL21077410 0.78 ADRB2 (0.36) ADRB2ADRB1ADRB3KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3588192-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, ELECTROPHOTOGRAPHIC APPARATUS, PROCESS CARTRIDGE, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CANON KK (JP) 2021-08-11 EP disclosed