SCHEMBL23741815

SCHEMBL23741815

c1ccc(-c2ccc(-n3c4ccc(-c5ccccc5)cc4c4c5c6ccccc6c6c7cc(-c8ccccc8)ccc7n(-c7ccc(-c8ccccc8)cc7)c6c5c5ccccc5c43)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
NR3C1 P04150 1/20 0.36
TSPO P30536 1/20 0.35
KMT2A Q03164 4/20 0.33
HDAC4 P56524 1/20 0.33
IL1R1 P14778 1/20 0.33
NR4A2 P43354 2/20 0.32
MEN1 O00255 3/20 0.32
MAPT P10636 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
MAOB P27338 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20311781 0.97 L3MBTL1 (0.39) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL23741537 0.97 L3MBTL1 (0.41) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL23741530 0.94 L3MBTL1 (0.42) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL2627599 0.92 L3MBTL1 (0.44) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL17451691 0.91 L3MBTL1 (0.46) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL20311782 0.90 NR3C1 (0.34) NR3C1TSPOALDH1A1HSP90AA1
SCHEMBL23741680 0.89 L3MBTL1 (0.44) L3MBTL1KDM4EATMKMT2AHDAC4
SCHEMBL17451669 0.88 L3MBTL1 (0.47) L3MBTL1KDM4EATMNR3C1TSPO
SCHEMBL19131684 0.88 L3MBTL1 (0.46) L3MBTL1KDM4EATMTSPOKMT2A
SCHEMBL16593139 0.87 ALDH1A1 (0.41) L3MBTL1KDM4EATMNR3C1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3339293-B1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2021-08-11 EP disclosed