Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234087 | 0.87 | TSHR (0.40) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL235139 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL238399 | 0.80 | HPGD (0.38) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL15901492 | 0.80 | TDP1 (0.50) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL237885 | 0.79 | THRB (0.47) | MTNR1AMTNR1BCACNA1BALDH1A1CHRNB2 | |
| SCHEMBL9337764 | 0.77 | HPGD (0.40) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL3180135 | 0.76 | TSHR (0.53) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL10526534 | 0.75 | POLB (0.43) | MTNR1AMTNR1BPOLBAPEX1HTT | |
| SCHEMBL28588409 | 0.74 | TSHR (0.50) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL13801021 | 0.74 | HPGD (0.44) | POLBAPEX1HTTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |