Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237432 | 0.87 | MTNR1A (0.41) | TSHRHPGDALDH1A1MAPTCYP1A2 | |
| SCHEMBL10526534 | 0.84 | POLB (0.43) | TSHRHPGDALDH1A1MAPTCYP1A2 | |
| SCHEMBL3180135 | 0.83 | TSHR (0.53) | TSHRHPGDALDH1A1MAPTCYP1A2 | |
| SCHEMBL238399 | 0.81 | HPGD (0.38) | TSHRHPGDALDH1A1MAPTCYP1A2 | |
| SCHEMBL9337764 | 0.81 | HPGD (0.40) | TSHRHPGDALDH1A1MAPTCYP1A2 | |
| SCHEMBL238596 | 0.78 | THRB (0.44) | TSHRALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL296808 | 0.77 | TSHR (0.55) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL235139 | 0.75 | MTNR1A (0.49) | TSHRHPGDCYP1A2CYP2D6ELANE | |
| SCHEMBL1685754 | 0.74 | TSHR (0.50) | TSHRHPGDALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9579874 | 0.73 | TSHR (0.49) | TSHRHPGDCYP1A2CYP2D6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |