Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.73 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | AXL | P30530 | 1/20 | 0.71 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.71 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.71 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.65 |
| ▸ | HPGDS | O60760 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014755 | 0.85 | RAB9A (0.66) | CYP19A1RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL30128572 | 0.84 | CYP19A1 (1.00) | CYP19A1RAB9ANPC1AXLPBRM1 | |
| SCHEMBL19051411 | 0.84 | CYP19A1 (1.00) | CYP19A1RAB9ANPC1AXLPBRM1 | |
| SCHEMBL6196239 | 0.84 | CYP19A1 (1.00) | CYP19A1RAB9ANPC1AXLPBRM1 | |
| SCHEMBL7495850 | 0.81 | RAB9A (1.00) | CYP19A1RAB9ANPC1AXLPBRM1 | |
| SCHEMBL17014786 | 0.81 | CYP19A1 (1.00) | CYP19A1RAB9ANPC1AXLPBRM1 | |
| SCHEMBL1741719 | 0.80 | CYP19A1 (0.79) | CYP19A1RAB9ANPC1KDM4EALDH1A1 | |
| [2,3'']Bipyridinyl SCHEMBL29389597 | 0.80 | CYP2A6 (1.00) | CYP19A1RAB9ANPC1KDM4EALDH1A1 | |
| [2,3'']Bipyridinyl SCHEMBL998601 | 0.80 | CYP2A6 (1.00) | CYP19A1RAB9ANPC1KDM4EALDH1A1 | |
| [2,3'']Bipyridinyl SCHEMBL29360744 | 0.80 | CYP2A6 (1.00) | CYP19A1RAB9ANPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210246109-A1 | POTENT AND SELECTIVE INHIBITORS OF CYTOCHROME P450 | CYP11B1, CYP1B1, CYP27A1 | CYP19A1 11/4885RAB9A 1418/4885NPC1 751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.