Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25110211 | 1.00 | DDB1 (0.42) | DDB1CRBNDAOOPRM1OPRL1 | |
| SCHEMBL25108271 | 1.00 | DDB1 (0.42) | DDB1CRBNDAOOPRM1OPRL1 | |
| SCHEMBL23572084 | 0.85 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL24779909 | 0.85 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL22892879 | 0.84 | DDB1 (0.42) | DDB1CRBNDAOOPRM1OPRL1 | |
| SCHEMBL21106899 | 0.80 | DDB1 (0.67) | DDB1CRBNOPRM1 | |
| SCHEMBL21106894 | 0.80 | DDB1 (0.67) | DDB1CRBNOPRM1 | |
| SCHEMBL21105892 | 0.80 | DDB1 (0.67) | DDB1CRBNOPRM1 | |
| SCHEMBL25162363 | 0.79 | DDB1 (0.38) | DDB1CRBN | |
| SCHEMBL25973037 | 0.79 | ADRB1 (0.40) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021158634-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |