Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25110211 | 1.00 | DDB1 (0.42) | DDB1CRBNDAOOPRM1OPRL1 | |
| SCHEMBL23744778 | 1.00 | DDB1 (0.42) | DDB1CRBNDAOOPRM1OPRL1 | |
| SCHEMBL23572084 | 0.85 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL24779909 | 0.85 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL22892879 | 0.84 | DDB1 (0.42) | DDB1CRBNDAOOPRM1OPRL1 | |
| SCHEMBL21106899 | 0.80 | DDB1 (0.67) | DDB1CRBNOPRM1 | |
| SCHEMBL21106894 | 0.80 | DDB1 (0.67) | DDB1CRBNOPRM1 | |
| SCHEMBL21105892 | 0.80 | DDB1 (0.67) | DDB1CRBNOPRM1 | |
| SCHEMBL25162363 | 0.79 | DDB1 (0.38) | DDB1CRBN | |
| SCHEMBL25973037 | 0.79 | ADRB1 (0.40) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230072658-A1 | SMARCA DEGRADERS AND USES THEREOF | SMARCA1, SMARCB1, SMARCE1 | DDB1 809/4885CRBN 9/4885DAO 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.